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VizHyal – Preservative Free Eye Drops – Sodium Hyaluronate 0.1% - for Treatment of Dry Eyes – 10ml

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Hydroxypropyl guar or combination product containing trehalose can be used for more severe symptoms as they can reduce inflammation and protect ocular surface. If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart. For patients with moderate episodic or chronic discomfort with or without environmental stress. Episodic visual symptoms which are annoying and/or activity-limiting.

Limited clinical data in pediatric patients with administration of dorzolamide (preserved formulation) three times a day are available. (For information regarding pediatric dosing see section 5.1). When used as monotherapy, the dose is one drop of dorzolamide in the conjunctival sac of the affected eye(s), three times daily.VIZhyal 0.1% is a sterile, ophthalmic solution that soothes and moisturizes the ocular surface to alleviate symptoms associated with moderate dry eyes, such as burning, irritation and foreign body sensation. VIZhyal 0.1% acts as a humectant on the eye, providing relief of dry eye conditions, including those associated with the use of PC, infrequent blinking, medical treatments, atmospheric pollution, air conditioning, central heating, wind and sun. The VIZHyal 0.2% trademark was assigned an Application Number # UK00003314178 by the UK Intellectual Property Office (UKIPO).

Recommend overnight treatment with a paraffin-based PF eye ointment: Xailin Night or Hylo-Night (formerly known as VitA-POS) or HydraMed Night Eye Ointments, 5g. If you develop allergic reactions including hives, swelling of the face, lips, tongue, and/or throat which may cause difficulty in breathing or swallowing, you should stop using this medicine and seek immediate medical advice. Patients should also be instructed that ocular solutions, if handled improperly, can become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions. Therapy with oral carbonic anhydrase inhibitors has been associated with urolithiasis as a result of acid-base disturbances, especially in patients with a prior history of renal calculi. Although no acid-base disturbances have been observed with dorzolamide, urolithiasis has been reported infrequently. Because dorzolamide is a topical carbonic anhydrase inhibitor that is absorbed systemically, patients with a prior history of renal calculi may be at increased risk of urolithiasis while using dorzolamide. Suitable for treatment of mild, moderate and severe dry eyes, providing long-lasting relief from eye discomfort and dryness; including post-surgery treatmentThe following side effects have been reported with dorzolamide preservative free either during clinical trials or during post-marketing experience: After you have used all doses there will be some Vizidor left in the bottle. You should not be concerned since an extra amount of Vizidor has been added and you will get the full amount of Vizidor that your doctor has prescribed. Do not attempt to use the excess medicine remaining in the bottle after you have completed the course of treatment. Carmellose (CMC) is a polysaccharide, a biological polymer, known as mucilage. It increases the residence of tears on the eye surface, as well as increasing the viscosity of the tear film. The properties of carmellose protects the eye against irritation, and moisturizes the ocular surface, thus relieving the sensation of discomfort caused by dry eye by creating a protective, viscoelastic shield.

Sodium Hyaluronate is a viscous polymer used for its moisturising and lubricating effects. Sodium Hyaluronate provides a protective, viscoelastic film across the ocular mucosa; which acts as an active barrier against external agents, and which helps to counteract symptoms of dry eye. Overall, this study did not reveal additional safety concerns in paediatric patients: approximately 26% (20% in dorzolamide monotherapy) of paediatric patients were observed to experience drug related adverse effects, the majority of which were local, non serious ocular effects such as ocular burning and stinging, injection and eye pain. A small percentage <4%, was observed to have corneal oedema or haze. Local reactions appeared similar in frequency to comparator. In post marketing data, metabolic acidosis in the very young particularly with renal immaturity/impairment has been reported.

Systane Balance (propylene glycol 0.6%) or Optive Plus (carboxymethylcellulose 0.5%, glycerine 1%, castor oil). 10ml, 6m expiry, contains preservative. If IOP was inadequately controlled on dorzolamide or timolol gel-forming solution monotherapy, a change was made to open-label therapy according to the following: 30 patients <2 years were switched to concomitant therapy with timolol gel-forming solution 0.25% daily and dorzolamide 2% t.i.d.; 30 patients ≥2 years were switched to 2% dorzolamide/0.5% timolol fixed combination b.i.d. (twice a day). Buffered solution with Calendula extract, Hamamelis extract, EDTA 0.12%, PHMB 0.0001%. Storage instructions irritation including redness, pain, eyelid crusting, transient myopia (which resolved upon discontinuation of therapy), corneal oedema, ocular hypotony, choroidal detachment following filtration surgery Put one drop in the affected eye(s) as directed by your doctor. Blink a few times so that the drop spreads over the eye. If you are not sure how to administer your medicine, ask your doctor, pharmacist or nurse.

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