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LG OFFICIAL England Ear buds TONE Free FA4 - LIMITED EDITION - True Wireless Bluetooth Earbuds with Meridian Sound, Hypoallergenic Medical-Grade Ear gels, Noise Reduction with a close fit. White

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out of 139 screening services submitted data, including 54 services that reported zero women at risk. The chance cut-off is set at 1 in 150 at term for the combined and quadruple tests. This means women with a result of greater than or equal to 1 in 150 (between 1 in 2 and 1 in 150) are in the higher chance group. These women must be offered an appointment to discuss their results and the option of prenatal diagnosis. The appointment can be face to face or virtual depending on the woman’s choice. transfer in before or at 14 weeks plus 1 day of pregnancy ( CRL less than or equal to 84.0mm) who have a result from a screening test performed elsewhere in the NHS in this pregnancy National performance of NB2 (see standard NBS-S06) in Q2 was 2.2%, similar to the previous quarter. The trend graph below shows that England NB2 performance is above the acceptable threshold of 2%. NB2 is a KPI where a lower performance is better.

The main aim of DQASS is to monitor and support the quality and effectiveness of Down’s syndrome, Edward’s syndrome and Patau’s syndrome screening in England. Workforce – education and training To provide assurance that individuals with a suspected or confirmed anomaly are referred in a timely manner and receive timely intervention. Definition If the NT cannot be measured, or the CRL measurement is greater than 84.0mm, the woman is offered the quadruple test. If accepted, this test can be performed when the baby’s head circumference ( HC) is between 101.0mm and 172.0mm. This is between 14 +2 and 20 +0 weeks. The blood sample can be taken from 14 +2 weeks. The combined test is offered in the first trimester to assess the chance of the baby having Down’s syndrome, Edwards’ syndrome or Patau’s syndrome, and is the test of choice.This standard excludes results based on increased NT measurement only. FASP recommends all women who make an informed choice to accept screening must have all components of the screening test completed - NT and biochemistry. Performance thresholds Screening strategy make sure all ultrasound providers participate in the Down’s syndrome quality assurance support service ( DQASS) out of 142 screening services submitted data, including 65 services that reported zero women at risk. Annually by 30 September for women who book with an estimated date of delivery within the previous financial year (1 April to 31 March). Review dates

make sure there is effective communication between maternity and ultrasound services, for example when interpreting services are needed To provide assurance that women with a suspected or confirmed unexpected finding are referred in a timely manner and receive timely intervention where appropriate. Definition For women who start screening between 18 weeks plus 0 days and 20 weeks plus 6 days and require a single further scan to complete screening where the image quality of the first scan is compromised by increased maternal body mass index ( BMI), uterine fibroids, abdominal scarring or sub-optimal fetal position.This standard provides assurance that the screen positive rate for the national programme remains within the defined range to minimise the number of women requiring an offer of an invasive diagnostic test. Definition The numerator and denominator include those completing fetal anomaly scan at 18 weeks plus 0 days to 23 weeks plus 0 days.

Log in to mySRA to apply, go to start a new application Apply for approval of a person as an authorised role holder A sample can be tested for T21 only, T18 and T13 only, or all 3 conditions depending on the woman’s choice. There are 2 pathway requirements specifications (Down’s syndrome, Edwards’ syndrome and Patau’s syndrome screening and 20-week screening scan) available for NHS providers as part of the public health functions exercised by NHS England ( NHSE).National performance of ST4a (see standard SCT-S05) in Q4 was 44.5%, lower than the previous 5 quarters. The trend graph below shows England ST4a performance since the KPI was first published in Q1 2019 to 2020. Thresholds have not yet been set for this KPI. Numerator: number of screening test results reported by the screening laboratory to the maternity service on or before 3 working days of sample receipt. Certificates of Good Standing (dated within three months of the application date), if regulated by another regulator.

Denominator: number of samples received in the genomic laboratory in the reporting period where the indication for QF-PCR testing was: NCARDRS data shows that coarctation of the aorta has the highest number of diagnoses of all cardiac conditions not currently part of FASP-S04. There are no changes to the ultrasound requirements and practitioners should continue to use the 3 vessel and trachea (3VT) view as part of the existing fetal cardiac protocol. Please be aware that this data covers the time period through the COVID-19 pandemic. Provider performance should therefore be interpreted with caution. Date of sample receipt in the laboratory is counted as day 1. Sample receipt is when the sample is recorded as received on the laboratory information management system.

Summary of changes

There is no intention to publish FA3 by individual maternity service. We are reviewing the data with the aim of publishing it national in the future. The proportion of screening test results reported on or before 3 working days of sample receipt. Rationale The 20-week screening scan is offered to screen for Edwards’ syndrome and Patau’s syndrome, and 11 physical conditions. Private screening National performance of FA2 in Q2 2021 to 2022 was 99.2%, slightly higher than the previous quarter. FA2 is collected 6 months (2 quarters) in arrears. The trend graph below shows that England FA2 performance has remained above the achievable threshold of 95% since 1 April 2017. Denominator: number of samples received for QFPCR testing where the indication for genetic testing is a higher chance T21, T18, T13 screening result issued in the reporting period

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